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1.Huang, Xueting, Xiuyuan Li, Haoran, Juanjuan Wang, Ming Ding, Lijun Wang, Lulu Li, Quanjiang Ji, Fen Qu, Hui Wang, Yingchun Xu, Xinxin Lu and Jing-Ren Zhang*. Capsule type defines the capacity of Klebsiella pneumoniae in evading Kupffer cell capture in the liver. PLOS Pathogens. In press.

2.Guo, Ziyi, Haoqi Yang, Jing-Ren Zhang, Wenwen Zeng, and Xiaoyu Hu. Leptin receptor signaling sustains metabolic fitness of alveolar macrophages to attenuate pulmonary inflammation. Science Advances. In press.

3.Haoran An, Chenyun Qian, Yijia Huang, Jing Li, Xianbin Tian, Jiaying Feng, Jiao Hu, Yujie Fang, Fangfang Jiao, Yuna Zeng, Xueting Huang, Xianbin Meng, Xue Liu, Xin Lin, Zhutian Zeng, Martin Guilliams, Alain Beschin, Yongwen Chen, Yuzhang Wu, Jing Wang, Marco R. Oggioni, John M. Leong, Jan-Willem Veening, Haiteng Deng, Rong Zhang, Hui Wang, Jiang Wu, Yan Cui, and Jing-Ren Zhang*. 2022. Functional vulnerability of liver macrophages to capsules defines virulence of blood-borne bacteria. Journal of Experimental Medicine 219:e20212032. DOI:10.1084/jem.20212032.

4.Menglan Zhou, Ziran Wang, Li Zhang, Timothy Kudinha, Haoran An, Chenyun Qian, Jiang Bin, Yao Wang, Ying-Chun Xu, Zhengyin Liu*, Hong Zhang* and Jing-Ren Zhang*. 2022. Serotype distribution, antimicrobial susceptibility, multilocus sequencing type and virulence of invasive Streptococcus pneumoniae in China: a six-year multi-center study. Frontiers in Microbiology 12:798750. DOI:10.3389/fmicb.2021.798750.

5.Qingqing Hu, Huichun Tong, Jing Wang, Pupu Ge, Lin Zhu, Cuihua Liu, Jing-Ren Zhang, Xiuzhu Dong. 2021. A novel aquaporin subfamily imports oxygen and contributes to pneumococcal virulence by controlling production and release of virulence factors. mBio 12:e01309-21. https://doi.org/10.1128/mBio.01309-21.

6.Zhang, Chengwang, Haoran An, Jiao Hu, Jing Li, Wenhao Zhang, Xun Lan, Haiteng Deng, and Jing-Ren Zhang*. 2021. MetR is a molecular adaptor for pneumococcal carriage in the healthy upper airway.  Molecular Microbiology 116:438-458. DOI:10.1111/MMI.14724.

7.Huang, Xueting, Juanjuan Wang, Jing Li, Yanni Liu, Xue Liu, Zeyao Li, Kurni Kurniyati, Yijie Deng, Guilin Wang, Joseph D. Ralph, Megan De Ste Croix, Sara Escobar-Gonzalez, Richard J. Roberts, Jan-Willem Veening, Xun Lan, Marco R. Oggioni*, Chunhao Li*, and Jing-Ren Zhang*. 2020. Prevalence of phase variable epigenetic invertons among host-associated bacteria. Nucleic Acids Research 48:11468-11485.  DOI:10.1093/nar/gkaa907.

8.Wang, Juanjuan, Jing-Wen Li, Yijia Huang, Shaolin Wang, and Jing-Ren Zhang*. 2020. Regulation of pneumococcal epigenetic and colony phases by multiple two-component regulatory systems. PLOS Pathogens 16 (3):e1008417. DOI:10.1371/journal.ppat.1008417.

9.Li, Jing.-Wen, Juanjuan Wang, Sofia Ruiz-Cruz, Manuel Espinosa, Jing-Ren Zhang*, and Alicia Bravo*. 2020. In vitro DNA inversions mediated by the PsrA site-specific tyrosine recombinase of Streptococcus pneumoniae. Frontiers in Molecular Biosciences 7:43. DOI:10.3389/fmolb.2020.00043.

10.Li, Jing-Wen, Jing Li, Juanjuan Wang, Chunhao Li, and Jing-Ren Zhang*. 2019. Molecular mechanisms of hsdS inversions in the cod locus of streptococcus pneumoniae. Journal of Bacteriology 201(6):e00581-18. DOI:10.1128/JB.00581-18.  Chosen by the editor as the Article of Significant Interest in This Issue, DOI:10.1128/JB.00023-19.

11.Liu, Yanni, Yuna Zeng, Yijia Huang, Gu L, Shaolin Wang, Chunhao Li, Donald A. Morrison, Haiteng Deng*, Jing-Ren Zhang*. 2019. HtrA鈥恗ediated selective degradation of DNA uptake apparatus accelerates termination of pneumococcal transformation. Molecular Microbiology 112锛1308-1325. DOI:10.1111/mmi.14364.

12.Li, Jing and Jing-Ren Zhang*. 2019. Phase variation of Streptococcus pneumoniae. Microbiology Spectrum 7(1). DOI:10.1128/microbiolspec.GPP3-0005-2018.

13.Zong, Yu, Fang Fang, Kirsten J. Meyer, Liguo Wang, Zhihao Ni, Hongying Gao. Kim Lewis, Jing-Ren Zhang, and Yu Rao. 2019. Gram-scale total synthesis of teixobactin promoting binding mode study and discovery of more potent antibiotics. Nature Communications 10:3268. DOI:10.1038/s41467-019-11211-y.

14.Zhang, Kai, Zhuan Qin, Yunjie Chang, Jun Liu, Michael G. Malkowski, Saimtun Shipa, Li Li, Weigang Qiu, Jing-Ren Zhang, and Chunhao Li*. 2019. Analysis of a flagellar filament cap mutant reveals that HtrA serine protease degrades unfolded flagellin protein in the periplasm of Borrelia burgdorferi.  Molecular Microbiology 111:1652-1670. DOI:10.1111/mmi.14243.

15.Wang, Xu, Yuna Zeng, Li Sheng, Peter Larson, Xue Liu, Xiaowen Zou, Shufang Wang, Kaijing Guo, Chen Ma, Gang Zhang, Huaqing Cui, David Ferguson, Yan Li, Jing-Ren Zhang*, and Courtney Aldrich*. 2019.  A cinchona alkaloid antibiotic that appears to target ATP synthase in Streptococcus pneumoniae. Journal of Medicinal Chemistry 62:2305-2332. DOI:10.1021/acs.jmedchem.8b01353.

16.Wang, Yang, Zhensong Wen, Xiaolei Pan, David E. Briles, Yongqun He, and Jing-Ren Zhang*. 2018. Novel immunoprotective proteins of Streptococcus pneumoniae identified by opsonophagocytosis killing screen. Infection and Immunity 86(9):e00423-18. DOI: 10.1128/IAI.00423-18.

17.He, Lihong, Dongyang Luo, Fan Yang, Chunhao Li, Xuegong Zhang, Haiteng Deng, and Jing-Ren Zhang*. 2018. Multiple domains of bacterial and human Lon proteases define substrate selectivity. Emerging Microbes and Infections (2018):149. DOI:10.1038/s41426-018-0148-4.

18.Kurniyati, Kurni, Jun Liu, Jing-Ren Zhang, Yunjiang Min, and Chunhao Li*. 2018. A pleiotropic role of FlaG homolog in regulating the cell morphogenesis and flagellar homeostasis at the cell poles of Treponema denticola. Cellular Microbiology 21:e12886. DOI:10.1111/cmi.12886.

19.Pan, Yushan *, Haoran An, Tong Fu, Shiyu Zhao, Chengwang Zhang, Genhui Xiao, Jing-Ren Zhang, Xinfang Zhao, Gongzheng Hu*. 2018. Characterization of Streptococcus pluranimalium from a cattle with mastitis by whole genome sequencing and functional validation. BMC Microbiology 18:182.  DOI:10.1186/s12866-018-1327-0

20.Xu, Miao, Huiping Lu, Young-Hee Lee, Y. Wu, Kewei Liu, Yuling Shi, Haoran An, Jing-Ren Zhang, Xiaohu Wang, Yuping Lai, and Chen Dong*. 2018. An Interleukin-25-mediated autoregulatory circuit in keratinocytes plays a pivotal role in psoriatic skin inflammation. Immunity 48:787-798 e4. DOI:10.1016/j.immuni.2018.03.019.

21.Liu, Xue, Jing-Wen Li, Zhixin Feng, Yongfu Luo, Jan-Willem Veening, and Jing-Ren Zhang*. 2017. Transcriptional repressor PvtR regulates phenotypic tolerance to vancomycin in Streptococcus pneumoniae. Journal of Bacteriology 199(14). pii:e00054-17. DOI:10.1128/JB.00054-17.

22.Li, Jing, Juanjuan Wang, Fangfang Jiao and Jing-Ren Zhang*. 2017. Observation of pneumococcal phase variation in colony morphology. Bio-protocol 7:Iss15. DOI:10.21769/BioProtoc.2434.

23.Yu, Yuanyuan, Jing-Wen Li, Long Jiang, Jing-Ren Zhang*, and Liansuo Zu*. 2017. Catalytic enantioselective aza-pinacol rearrangement. Angewandte Chemie International Edition English 56:9217-9221. DOI:10.1002/anie.201705539.

24.Chen, Fei, Guolin Cui, Shuxia Wang, Manoj K. Mohan Nair, Lihong He, Xinyi Qi, Xiangmin Han, Hanqi Zhang, Jing-Ren Zhang*, and Jingliang Su*.  2017. Outer membrane vesicle-associated lipase FtlA enhances cellular invasion and virulence in Francisella tularensis LVS. Emerging Microbes and Infections 6:e66. DOI:10.1038/emi.2017.53.

25.Liu, Bo, Xue Liu, Jing-Ren Zhang*, and Gang Liu*. 2017. A natural lipotrisaccharide and its derivatives selectively lyse Streptococcus pneumoniae via interaction with cell membrane.  ACS Infectious Diseases 3:438-453. DOI:10.1021/acsinfecdis.7b00008.

26.Liu, Xue, Clement Gallay, Morten Kjos, Amau Domenech, Jelle Slager, Sebastiaan P. van Kessel, Kevin Knoops, Robin A. Sorg, Jing-Ren Zhang, and Jan-Willem Veening*. 2017. High-throughput CRISPRi phenotyping in Streptococcus pneumoniae identifies new essential genes involved in cell wall synthesis and competence development. Molecular Systems Biology 13:931. DOI:10.15252/msb.20167449.

27.Li, Jing Jing-Wen Li, Zhixin Feng, Juanjuan Wang, Haoran An, Yanni Liu, Yang Wang, Kailing Wang, Xuegong Zhang, Zhun Miao, Wenbo Liang, Robert Sebra, Guiling Wang, Wen-Ching Wang, and Jing-Ren Zhang*. 2016. Epigenetic switch driven by DNA inversions dictates phase variation in Streptococcus pneumoniae. PLOS Pathogens 12: e1005762. DOI:10.1371/journal.ppat.1005762. Highlighted in Nature Reviews Microbiology DOI:10.1038/nrmicro.2016.122.

28.Wen, Zhensong, Yanni Liu, Fen Qu, and Jing-Ren Zhang*. 2016. Allelic variation of the capsule promoter diversifies encapsulation and virulence in Streptococcus pneumoniae. Scientific Reports 6:30176. DOI: 10.1038/srep30176.

29.Li, Guilin, Zhuowen. Liang, Xiatai Wang, Yonghong Yang, Zhujun Shao, Ma Li, Yueyun Ma, Fen Qu, Donald A. Morrison, and Jing-Ren Zhang*. 2016. Addiction of hyper-transformable pneumococcal isolates to natural transformation for in vivo fitness and virulence. Infection and Immunity 84:1887-1901. DOI:10.1128/IAI.00097-16.

30.He, Lihong, Manoj K. Mohan Nair, Yuling Chen, Xue Liu, Mengyun Zhang, Karsten R. O. Hazlett, Haiteng Deng*, and Jing-Ren Zhang*.  2016. The protease locus of Francisella tularensis LVS is required for stress tolerance and infection of mammalian host. Infection and Immunity 84:1387-402. DOI:10.1128/IAI.00076-16.

31.Bai, Xiao-Hui, Qiong Li, Yong-Liang Jiang, Jing-Ren Zhang*, Yuxin Chen*, and Cong-Zhao Zhou*. 2016. Structural comparison and simulation of pneumococcal peptidoglycan hydrolase LytB.  Methods in Molecular Biology. 1440:271-83. DOI:10.1007/978-1-4939-3676-2_19.

32.Yang, Hongzhi, Xue Liu, Qingong Li, Longbo Li, Jing-Ren Zhang*,  and Yefeng Tang*. 2016. Total synthesis and preliminary SAR study of (+/-)-merochlorins A and B. Organic & Biomolecular Chemistry. 14:198-205. DOI: 10.1039/c5ob01946j.

33.Yang, Tao, Gong Chen, Zitai Sang, Yuanyuan Liu, Xiaoyan Yang, Ying Chang, Haiyue Long, Wei Ang, Jianying Tang, Zhenling Wang*, Guobo Li, Shengyong Yang, Jing-Ren Zhang, Yuquan Wei, and Youfu Luo*. 2015. Discovery of a teraryl oxazolidinone compound (S)-N-((3-(3-fluoro-4-(4-(pyridin-2-yl)-1H-pyrazol-1-yl)phenyl)-2-oxooxazolidin-5 -yl)methyl)acetamide phosphate as a novel antimicrobial agent with enhanced safety profile and efficacies. Journal of Medical Chemistry 58:6389-409. DOI: 10.1021/acs.jmedchem.5b00152.

34.Wang, Lei, Yong-Liang Jiang, Jing-Ren Zhang, Cong-Zhao Zhou, and Yuxin Chen*. 2015. Structural and enzymatic characterization of the choline kinase LicA from Streptococcus pneumoniae. PLoS One 10:e0120467. DOI:10.1371/journal.pone.0120467.

35.Wen, Zhensong, Odeniel Sertil, Yongxin Chen, Shanshan Zhang, Xue Liu, Wen-Ching Wang, and Jing-Ren Zhang*.  2015. The sequence elements upstream of the core promoter are necessary for the full transcription of the capsule gene operon in Streptococcus pneumoniae strain D39. Infection and Immunity 83:1957-1972. DOI:10.1128/IAI.02944-14.

36.Achila, David, Aizhou Liu, Rahui Banerjee, Yue Li, Erik Martinez-Hackert, Jing-Ren Zhang*, and Honggao Yan*. 2015. Structural determinants of host specificity of complement factor H recruitment by Streptococcus pneumoniae. Biochemical Journal 465:325-335. DOI:10.1042/BJ20141069.

37.Feng, Zhixin., Jing Li, Jing-Ren Zhang*, and Xuegong Zhang*. 2014. qDNAmod: a statistical model based tool to reveal intercellular heterogeneity of DNA modification from SMRT sequencing data. Nucleic Acids Research 42:13488-13499. DOI:10.1093/nar/gku1097.

38.Zhu, Deyu, Lijun Wang, Guijun Shang, Xue Liu, Jing Zhu, Defen Lu, Lei Wang, Biao Kan, Jing-Ren Zhang, and Ye Xiang. 2014. Structural biochemistry of a Vibrio cholerae dinucleotide cyclase reveals cyclase activity regulation by folates. Molecular Cell 55:931-937. DOI:10.1016/j.molcel.2014.08.001.

39.Zeng Xian-Fei, Yueyun Ma, Liu Yang, Lei Zhou, Yijun Xin, Liang Chang, Jing-Ren Zhang, and Xiaoke Hao*. 2014. A C-terminal truncated mutation of licC attenuates the virulence of Streptococcus pneumoniae. Research in Microbiololgy 165: 630-638. DOI:10.1016/j.resmic.2014.09.002.

40.Song, Yongxiang, Qinglian Li, Xue Liu, Yuchan Chen, Yun Zhang, Aijun Sun, Weimin Zhang, Jing-Ren Zhang, and Jianhua Ju*. 2014. Cyclic hexapeptides from the deep South China Sea-derived Streptomyces scopuliridis SCSIO ZJ46 active against pathogenic Gram-positive bacteria. Journal of Natural Products 77:1937-1941. DOI:10.1021/np500399v.

41.Yang, Yi-Hu, Yong-Liang Jiang, Juan Zhang, Lei Wang, Xiao-Hui Bai, Shi-Jie Zhang, Yan-Min Ren, Na Li, Yonghui Zhang, Zhiyong Zhang, Qingguo Gong, Yide Mei, Ting Xue, Jing-Ren Zhang, Yuxin Chen*, and Cong-Zhao Zhou*. 2014. Structural insights into SraP-mediated Staphylococcus aureus adhesion to host cells. PLOS Pathogens 10:e1004169. DOI:10.1371/journal.ppat.1004169.

42.Pan, Xiaolei, Yang Yang, and Jing-Ren Zhang*.  2014. Molecular basis of host specificity in human pathogenic bacteria. Emerging Microbes and Infections 3:e23. DOI:10.1038/emi.2014.23.

43.Gupta, R., Jun Yang, Y. Dong, E. Swiatlo, Jing-Ren Zhang, Dennis W. Metzger, and Guangchun Bai*. 2013. Deletion of arcD in Streptococcus pneumoniae D39 impairs its capsule and attenuates virulence. Infection and Immunity 81:3903-3911.

44.Qaidi, Samir E., Jun Yang, Jing-Ren Zhang, Dennis W. Metzger, and Guangchun Bai*. 2013. The vitamin B6 biosynthesis pathway in Streptococcus pneumoniae is controlled by pyridoxal 5鈥-phosphate and the transcription factor PdxR, and impacts on ear infection. Journal of Bacteriology 195:2187-2196.


瀛︽湳鑽h獕涓庡鍔

2008鑽h幏涓浗鍥藉鑷劧绉戝鍩洪噾娴峰鎴栨腐銆佹境闈掑勾瀛﹁呭悎浣滅爺绌跺熀閲戯紙鏉板嚭闈掑勾B绫伙級锛

2007鑽h幏缇庡浗寰峰厠钀ㄦ柉澶у绯荤粺Chancellor鈥檚 Entrepreneurship and Innovation Award in Category II锛

1997鑽h幏缇庡浗寰敓鐗╁浼歍he Raymond W. Sarber Award锛

1997鑽h幏缇庡浗寰峰厠钀ㄦ柉澶у浼戞柉鏁﹀垎鏍he Presidential Fellowship Award銆



寮璁璇剧▼

鍖诲寰敓鐗╁锛堟竻鍗庡ぇ瀛︾簿鍝佽绋嬶級

楂樼骇寰敓鐗╁

鐥呭師瀹夸富浜掍綔

寰敓鐗╁

鐢熺墿宸ョ▼鍓嶆部


鍏朵粬绀句細鑱屽姟

1.銆奆rontiers in Microbiology銆嬫潅蹇楋紝鍓紪杈戯紱

2.銆奅merging Microbes and Infection銆嬶紝缂栬緫锛

3.銆奐ournal of Clinical Microbiology銆嬬紪濮旓紱

4.涓浗鑷劧绉戝鍩洪噾銆佺編鍥絅IH鐮旂┒鍩洪噾銆佽嫳鍥組RC鐮旂┒鍩洪噾璇勫涓撳锛

5.涓崕棰勯槻鍖诲浼氭劅鏌撴х柧鐥呴槻鎺у垎浼氾紝濮斿憳锛

6.涓浗寰敓鐗╁崗浼氬垎鏋愬井鐢熺墿瀛﹀垎浼氾紝鍓悊浜嬶紱

7.搴峰笇璇虹敓鐗╄偂浠藉叕鍙哥瀛﹂【闂鍛樹細椤鹃棶銆


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